Our Publications

Preclinical models of soft tissue sarcomas – generation and applications to enhance.  translational research
Pasquali S*, Moura DS*, Danks MR, Manasterski PJ, Zaffaroni N, Stacchiotti S, Mondaza-Hernandez  JL, Kerrison W, Martin-Broto J, Huang PH, Brunton VG. Preclinical models of soft tissue sarcomas – generation and applications to enhance.  translational research.  Critical Reviews in Oncology / Hematology. 2025 Mar:207:104621. doi: 10.1016/j.critrevonc.2025.104621. Epub 2025 Jan 15.

Which sarcoma requires PD1/PDL1 inhibitors, and what should be the best scheme? Present status and next steps
Javier Martin-Broto, David S Moura, Nadia Hindi. Which sarcoma requires PD1/PDL1 inhibitors, and what should be the best scheme? Present status and next steps.  Curr Opin Oncol. 2025 Jul 1;37(4):331-338. doi: 10.1097/CCO.0000000000001149.

High throughput screening identifies activity of histone deacetylase inhibitors in patient-derived models of soft tissue sarcoma
Danks MR, Manasterski PJ, Beetham H, Dawson JC, Elliott RJR, Culley J, Krishna R, Ewing A, Thomson JP, Muir M, Oswald AJ, Huang PH, Nixon I, Carragher NO, Brunton VG. High throughput screening identifies activity of histone deacetylase inhibitors in patient-derived models of soft tissue sarcoma. Cancer Biol Ther 2025 Dec 31;26(1):2589666. doi: 10.1080/15384047.2025.2589666.

Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Manasterski PJ, Danks MR, Thomson JP, Muir M, Lee M, Dawson JC, Amaral AT, Diaz-Martin J, Moura DS, Martin-Broto J, Alsaadi A, Salter DM, Oswald AJ, Grimes G, Hayward L, Hupp TR, Sisley K, Huang PH, Carragher NO, Brunton VG. Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma. Mol Oncol. 2025 May 26. doi: 10.1002/1878-0261.70059

OsiriXGPT: An Innovative AI Co-pilot Plug-In for Seamless Deployment of Generative AI Models in Scan-to-Scan Reporting Workflows
Candito, Antonio, Timothy Sum-Hon Mun, Richard Holbrey, Simon Doran, Christina Messiou, Dow-Mu Koh, and Matthew D. Blackledge. "OsiriXGPT: An Innovative AI Co-pilot Plug-In for Seamless Deployment of Generative AI Models in Scan-to-Scan Reporting Workflows." Journal of Imaging Informatics in Medicine (2025): 1-17. doi: 10.1007/s10278-025-01712-2

The G-quadruplex experimental drug QN-302 impairs liposarcoma cell growth by inhibiting MDM2 expression and restoring p53 levels
Tosoni B, Naghshineh E, Zanin I, Gallina I, Di Pietro L, Cleris L, Nadai M, Lecchi M, Verderio P, Pratesi P, Pasquali S, Zaffaroni N, Neidle S, Folini M, Richter SN. The G-quadruplex experimental drug QN-302 impairs liposarcoma cell growth by inhibiting MDM2 expression and restoring p53 levels. Nucleic Acids Res. 2025 Feb 8;53(4):gkaf085. doi: 10.1093/nar/gkaf085. PMID: 39970293

Robotic MRI/CT Guided Multiregional 'smart' Biopsy for Characterization of Tumor Heterogeneity: A Prospective Development Study
Johnston EW, Winfield JM, Arthur A, Blackledge M, Banerjee U, Basso J, Chowdhury A, Hannay J, Hayes A, Kelly-Morland C, Napolitano A, Richardson C, Smith M, Strauss D, Koh DM, Jones RL, Thway K, Huang P, Messiou C, Fotiadis N.  Robotic MRI/CT Guided Multiregional 'smart' Biopsy for Characterization of Tumor Heterogeneity: A Prospective Development Study. Acad Radiol. 2025 Feb;32(2):1100-1107. doi: 10.1016/j.acra.2024.10.055. Epub 2024 Nov 26

CINSARC and Sarculator in Patients with Primary Retroperitoneal Sarcoma: A Combined Analysis of Single-Institution Data and the EORTC-STBSG-62092 Trial (STRASS)
Callegaro D, Tinè G, Oppong FB, Nzokirantevye A, Litière S, Percio S, Carenzo A, De Cecco L, Chibon F, Brich S, Bertolotti A, Collini P, Frezza AM, Huang P, Haas R, Bonvalot S, van Houdt WJ, Miceli R, Pasquali S, Gronchi A. CINSARC and Sarculator in Patients with Primary Retroperitoneal Sarcoma: A Combined Analysis of Single-Institution Data and the EORTC-STBSG-62092 Trial (STRASS). Clin Cancer Res. 2025 Aug 1;31(15):3239-3248. doi: 10.1158/1078-0432.CCR-25-0099

Proteomic Features of Adolescents and Young Adults with Soft Tissue Tumours
Tam YB, Low K, Ps H, Chadha M, Burns J, Wilding CP, Arthur A, Chen TW, Thway K, Sadanandam A, Jones RL, Huang PH. (2024) Proteomic Features of Adolescents and Young Adults with Soft Tissue Tumours. Communications Medicine. 2024 May 18;4(1):93. doi: 10.1038/s43856-024-00522-x

Pathologic complete response in patients with localized soft tissue sarcoma treated with neoadjuvant therapy and its correlation with clinical outcomes: A systematic review
Boulouta A, Kyriazoglou A, Kotsantis I, Economopoulou P, Anastasiou M, Pantazopoulos A, Kyrkasiadou M, Moutafi M, Gavrielatou N, Zazas E, Caglar C, Nixon I, Tolia M, Kavourakis G, Psyrri A.  Pathologic complete response in patients with localized soft tissue sarcoma treated with neoadjuvant therapy and its correlation with clinical outcomes: A systematic review. Cancer Treat Rev. 2024 Aug 24;130:102820. PMID: 39216184. DOI: 10.1016/j.ctrv.2024.102820.

2030: Impact & usability of virtual reality on emotional wellbeing of sarcoma patients: VR-SARC study
McLeod C, Abraham A, Chapman L, Cain J, Scott J, Vohra S, Syed R, Nixon I. (2024).  2030: Impact & usability of virtual reality on emotional wellbeing of sarcoma patients: VR-SARC study. Radiotherapy and Oncology.194. S2109-S2111. 10.1016/S0167-8140(24)02321-1

UK guidelines for the management of soft tissue sarcomas
Hayes A, Nixon I, Strauss D, Seddon B, Desai A, Benson C, Judson I, Dangoor A.  (2024).  UK guidelines for the management of soft tissue sarcomas. British Journal of Cancer. 10.1038/s41416-024-02674-y

Prospective evaluation of quantitative response parameter in patients with Gastrointestinal Stroma Tumor undergoing tyrosine kinase inhibitor therapy-Impact on clinical outcome
Meyer M, Ota H, Messiou C, Benson C, Henzler T, Mattonen SA, Marin D, Bartsch A, Schoenberg SO, Riedel RF, Hohenberger P.  Prospective evaluation of quantitative response parameter in patients with Gastrointestinal Stroma Tumor undergoing tyrosine kinase inhibitor therapy-Impact on clinical outcome. Int J Cancer. 2024 Jul 18. doi: 10.1002/ijc.35094

Current Management of Desmoid Tumors: A Review
Kasper B, Baldini EH, Bonvalot S, Callegaro D, Cardona K, Colombo C, Corradini N, Crago AM, Dei Tos AP, Dileo P, Elnekave E, Erinjeri JP, Navid F, Farma JM, Ferrari A, Fiore M, Gladdy RA, Gounder M, Haas RL, Husson O, Kurtz JE, Lazar AJ, Orbach D, Penel N, Ratan R, Raut CP, Roland CL, Schut AW, Sparber-Sauer M, Strauss DC, Van der Graaf WTA, Vitellaro M, Weiss AR, Gronchi A; Desmoid Tumor Working Group. Current Management of Desmoid Tumors: A Review. JAMA Oncol. 2024 Aug 1;10(8):1121-1128. doi: 10.1001/jamaoncol.2024.1805

GDF-15 predicts epithelioid hemangioendothelioma aggressiveness and is down-regulated by sirolimus through ATF4/ATF5 suppression
Stacchiotti S, Martini S, NapolitanoS, Frezza AM, Beretta A, Percio S, Lecchi M, Tortoreto M, Barisella M, Collini P, Dagrada GP, Merlini A, Huang PH, Jenks A, Jones RL, Tap WD, Ingrosso M, Morosi C, Brich S, Giani C, Verderio P, Casali PG, Leonard H, Gronchi A, Zuco V, Zaffaroni N. GDF-15 predicts epithelioid hemangioendothelioma aggressiveness and is down-regulated by sirolimus through ATF4/ATF5 suppression. Clin Cancer Res. 2024 Sep 16. doi:10.1158/1078-0432.CCR-23-3991

Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall
Chadha M, Iadecola S, Jenks A, Pankova V, Tam YB, Burns J, Arthur A, Wilding CP, Chen L, Chudasama P, Callegaro D, Strauss DC, Thway K, Gronchi A, Jones RL, Miceli R, Pasquali S, Huang PH. Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall. Cancer Med. 2024 Jul;13(14):e70026. doi: 10.1002/cam4.70026

Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine
Chowdhury A, Thway K, Pasquali S, Callegaro D, Gronchi A, Jones RL, Huang PH. Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine. Curr Treat Options Oncol. 2024 Aug;25(8):1124-1135. doi: 10.1007/s11864-024-01244-x

Phase Ib Study for the Combination of Doxorubicin, Dacarbazine, and Nivolumab as the Upfront Treatment in Patients With Advanced Leiomyosarcoma: A Study by the Spanish Sarcoma Group (GEIS)
Javier Martin-Broto; Roberto Diaz-Beveridge; David Moura; Rafael Ramos; Javier Martinez-Trufero; Irene Carrasco; Ana Sebio; Enrique Gonzalez-Billalabeitia; Antonio Gutierrez; Javier Fernandez-Jara; Laura Hernandez-Vargas; Josefina Cruz; Claudia Valverde; and Nadia Hindi. Phase Ib Study for the Combination of Doxorubicin, Dacarbazine, and Nivolumab as the Upfront Treatment in Patients With Advanced Leiomyosarcoma: A Study by the Spanish Sarcoma Group (GEIS).  Journal of Clinical Oncology, 2025 Jan 20;43(3):297-307. doi: 10.1200/JCO.24.00358

HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on Sarcomas (GEIS) study
Moura DS, Mondaza-Hernandez JL, Sanchez-Bustos P, Peña-Chilet M, Cordero-Varela JA, Lopez-Alvarez M, Carrillo-Garcia J, Martin-Ruiz M, Romero-Gonzalez P, Renshaw-Calderon M, Ramos R, Marcilla D, Alvarez-Alegret R, Agra-Pujol C, Izquierdo F, Ortega-Medina L, Martin-Davila F, Hernandez-Leon CN, Romagosa C, Salgado MAV, Lavernia J, Bagué S, Mayodormo-Aranda E, Alvarez R, Valverde C, Martinez-Trufero J, Castilla-Ramirez C, Gutierrez A, Dopazo J, Hindi N, Garcia-Foncillas J, Martin-Broto J. HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on Sarcomas (GEIS) study.  Cell Mol Life Sci. 2024 May 17;81(1):219. doi: 10.1007/s00018-024-05250-y

Multi-center external validation of an automated method segmenting and differentiating atypical lipomatous tumors from lipomas using radiomics and deep-learning on MRI
Spaanderman DJ, Hakkesteegt SN, Hanff DF, Schut ARW, Schiphouwer LM, Vos M, Messiou C, Doran SJ, Jones RL, Hayes AJ, Nardo L, Abdelhafez YG, Moawad AW, Elsayes KM, Lee S, Link TM, Niessen WJ, van Leenders GJLH, Visser JJ, Klein S, Grünhagen DJ, Verhoef C, Starmans MPA. Multi-center external validation of an automated method segmenting and differentiating atypical lipomatous tumors from lipomas using radiomics and deep-learning on MRI.  EClinicalMedicine. 2024 Sep 18;76:102802. doi: 10.1016/j.eclinm.2024.102802. eCollection 2024 Oct

Clinical Implications and Molecular Features of Extracellular Matrix Networks in Soft Tissue Sarcomas
Pankova V, Krasny L, Kerrison W, Tam YB, Chadha M, Burns J, Wilding CP, Chen L, Chowdhury A, Perkins E, Lee ATJ, Howell L, Guljar N, Sisley K, Fisher C, Chudasama P, Thway K, Jones RL, Huang PH.  Clinical Implications and Molecular Features of Extracellular Matrix Networks in Soft Tissue Sarcomas. Clin Cancer Res. 2024 Aug 1;30(15):3229-3242. doi: 10.1158/1078-0432.CCR-23-3960.

Novel Therapeutics in Soft Tissue Sarcoma
Mavroeidis L, Napolitano A, Huang P, Jones RL. Novel Therapeutics in Soft Tissue Sarcoma. Cancers (Basel). 2024 Dec 24;17(1):10. doi: 10.3390/cancers17010010. PMID: 39796641

Radiomic features of primary retroperitoneal sarcomas: a prognostic study
Pasquali S, Iadecola S, Vanzulli A, Infante G, Bologna M, Corino V, Greco G, Vigorito R, Morosi C, Beretta A, Percio S, Vallacchi V, Collini P, Sanfilippo R, Fabbroni C, Stacchiotti S, Fiore M, Huang P, Benelli M, Mainardi L, Miceli R, Gronchi A, Callegaro D. Radiomic features of primary retroperitoneal sarcomas: a prognostic study. Eur J Cancer. 2024 Dec;213:115120. doi: 10.1016/j.ejca.2024.115120.

The proteomic landscape of soft tissue sarcomas
Jessica Burns, Christopher P. Wilding, Lukas Krasny, Xixuan Zhu, Madhumeeta Chadha, Yuen Bun Tam, Hari PS, Aswanth H. Mahalingam, Alexander T. J. Lee, Amani Arthur, Nafia Guljar, Emma Perkins, Valeriya Pankova, Andrew Jenks, Vanessa Djabatey, Cornelia Szecsei, Frank McCarthy, Chanthirika Ragulan, Martina Milighetti, Theodoros I. Roumeliotis, Stephen Crosier, Martina Finetti, Jyoti S. Choudhary, Ian Judson, Cyril Fisher, Eugene F. Schuster,Anguraj Sadanandam, Tom W. Chen, Daniel Williamson, Khin Thway, Robin L. Jones, Maggie C. U. Cheang, Paul H. Huang.  The proteomic landscape of soft tissue sarcomas. Nat Commun 14, 3834 (2023). https://doi.org/10.1038/s41467-023-39486-2

Organ Infiltration and Patient Risk After Multivisceral Surgery for Primary Retroperitoneal Liposarcomas
Improta L, Pasquali S, Iadecola S, Barisella M, Fiore M, Radaelli S, Colombo C, Alloni R, Callegaro D, Valeri S, Miceli R, Gronchi A. Organ Infiltration and Patient Risk After Multivisceral Surgery for Primary Retroperitoneal Liposarcomas. Ann Surg Oncol. 2023 Mar 17. https://doi.org/10.1245/s10434-023-13314-9

Preoperative Neutrophil-to-Lymphocyte Ratio and a New Inflammatory Biomarkers Prognostic Index for Primary Retroperitoneal Sarcomas: Retrospective Monocentric Study
Fiore M, Ljevar S, Pasquali S, Morelli D, Callegaro D, Sanfilippo R, Barisella M, Sangalli C, Miceli R, Gronchi A. Preoperative Neutrophil-to- Lymphocyte Ratio and a New Inflammatory Biomarkers Prognostic Index for Primary Retroperitoneal Sarcomas: Retrospective Monocentric Study. Clin Cancer Res. 2023 Feb 1;29(3):614-620.https://doi.org/10.1158/1078-0432.CCR-22-2897

Phase II Trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A
Javier Martin-Broto, Jeronimo Martinez-Garcia, David S. Moura, Andres Redondo, Antonio Gutierrez, Antonio Lopez-Pousa, Javier Martinez-Trufero, Isabel Sevilla, Roberto Diaz-Beveridge, Maria Pilar Solis-Hernandez, Amancio Carnero, Marco Perez, David Marcilla, Jesus García-Foncillas, Pablo Romero, Javier Fernandez-Jara, Daniel Lopez-Lopez, Ivan Arribas, Nadia Hindi.  Phase II Trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A. Phase II Trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A. Signal Transduction and Targeted Therapy. 2023 Oct 25. doi: 10.1038/s41392-023-01661-8

Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models
Payá-Milans M, Peña-Chilet M, Loucera C, Esteban-Medina M, Dopazo J.  Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models. Int J Mol Sci. 2023 Sep 29;24(19):14732. doi: 10.3390/ijms241914732   https://pubmed.ncbi.nlm.nih.gov/37834179/

The biology and treatment of leiomyosarcomas
Kerrison, W., Thway, K., Jones, R.L., and Huang, P.H. (2023).  The biology and treatment of leiomyosarcomas. Crit Rev Oncol Hematol. 184:103995. doi: 10.1016/j.critrevonc.2023.103955

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis
Arthur A, Orton MR, Emsley R, Vit S, Kelly-Morland C, Strauss D, Lunn J, Doran S, Lmalem H, Nzokirantevye A, Litiere S, Bonvalot S, Haas R, Gronchi A, Van Gestel D, Ducassou A, Raut CP, Meeus P, Spalek M, Hatton M, Le Pechoux C, Thway K, Fisher C, Jones R, Huang PH, Messiou C. A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis. Lancet Oncol. 2023 Nov;24(11):1277-1286. doi: 10.1016/S1470-2045(23)00462-x. PMID: 37922931

Pseudoprogression in patients with uterine leiomyosarcoma treated with first-line single-agent doxorubicin
Howroyd LR, Cornell I, Benson C, Napolitano A, Blackledge M, Sumhonmun T, Moskovic E, Kelly-Morland C, Adejolu M, Jones RL, Messiou C.  Pseudoprogression in patients with uterine leiomyosarcoma treated with first-line single-agent doxorubicin. Eur J Cancer. 2023 Oct;192:113261. doi: 10.1016/j.ejca.2023.113261. Epub 2023 Jul 27.PMID: 37604068

Oncologic outcomes of surgically managed primary pelvic soft tissue sarcoma; tumour biology or surgical constraints of the true pelvis?
Khan M, Wilkerson H, Vassos N, Hannay JA, Thway K, Messiou C, Hayes AJ, Strauss DC, Smith MJ.  Oncologic outcomes of surgically managed primary pelvic soft tissue sarcoma; tumour biology or surgical constraints of the true pelvis? Eur J Surg Oncol. 2023 May;49(5):941-949. doi: 10.1016/j.ejso.2022.12.005. Epub 2022 Dec 17.PMID: 36566120

Test-retest repeatability of data-driven radiomic features derived from a deep-learning model: Diffusion-weighted MRI of soft-tissue sarcoma
Timothy S.H. Mun, Imogen Thrussell, Jessica M. Winfield, Amani Arthur, David J. Collins, Dow-Mu Koh, Paul H. Huang, Simon J. Doran, Christina Messiou, Matthew D. Blackledge. Joint Annual Meeting International Society for Magnetic Resonance in Medicine (ISMRM) - European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) and International Society for MR Radiographers & Technologists (ISMRT) 31st Annual Meeting 9 May 2022 (Accepted Paper)

OsiriXgrpc: Rapid development and deployment of state-of-the-art artificial intelligence for clinical practice
Timothy S.H. Mun, Richard Holbrey, Sue Chua, Paul H. Huang, Christina Messiou, Simon J. Doran, Matthew D. Blackledge. Association for the Advancement of Artificial Intelligence (AAAI) 2022, AI to Accelerate Science and Engineering (AI2ASE) Workshop  28 February 2022 (Accepted Paper)

Current Status and Future Directions of Immunotherapies in Soft Tissue Sarcomas
William G. J. Kerrison, Alexander T. J. Lee, Khin Thwa, Robin L. Jones, Paul H. Huang. Biomedicines 28 February 2022, 10(3):573. https://doi.org/10.3390/biomedicines10030573

Integrating the OHIF Viewer into XNAT: Achievements, Challenges and Prospects for Quantitative Imaging Studies
Simon J. Doran, Mohammad Al Sa’d, James A. Petts, James Darcy, Kate Alpert, Woonchan Cho, Lorena Escudero Sanchez, Sachidanand Alle, Ahmed El Harouni, Brad Genereaux, Erik Ziegler, Gordon J. Harris, Eric O. Aboagye, Evis Sala, Dow-Mu Koh and Dan Marcus. Tomography 11 February 2022, 8(1):497-512.  https://doi.org/10.3390/tomography8010040

SELNET clinical practice guidelines for soft tissue sarcoma and GIST
Jean-Yves Blay, Nadia H. Muñiz, Julien Bollard, Samuel Aguiar, Martin Angel, Beatriz Araya, Ronald Badilla-González, Daniel Bernabeu, Fernando A.B. Campos, Claudia H.S. Caro-Sánchez,  Berenice Carvajal, Alvaro Carvajal Montoya, Sandro Casavilca-Zambrano, Victor Castro-Oliden, Matías Chacón, Miguel Clara, Paola Collini, Raquel  Correa Genoroso, Felipe D. Costa, Mario Cuellar, Angelo P. dei Tos, Hugo R. Dominguez Malagon, Davide M. Donati, Armelle Dufresne, Mikael Eriksson, Macarena Farias-Loza, P. Fernandez, Anna M. Frezza, Tommaso Frisoni, Dorian Y. Garcia-Ortega, Hans Gelderblom, Francois Gouin, María  C. Gómez-Mateo, Alessandro Gronchi, Juan C. Haro-Varas, Lourdes Huanca, Natalia Jiménez-Brenes, Marie  Karanian, Bernd Kasper, Bruna B. Lopes David, Antonio Lopez-Pousa, Guido Lutter, Héctor  Martinez-Said, Jorge L. Martinez-Tlahuel, Celso A.L.D. Mello, Jose M. Morales-Pérez, David S. Moura, Antonio G. Nascimento, Eduardo J. Ortiz-Cruz, Emanuela Palmerini, Shreyaskumar Patel, Yanina Pfluger, Salvatore Provenzano, Alberto Righi, Andrés Rodriguez, Rafael S. Salas, Tiago T.G. Santos, Katia Scotlandi, Tomas J. Soule, Silvia Stacchiotti, Claudia Valverde, Federico Waisberg, Esteban Zamora Estrada, Javier Martín-Broto. Cancer Treatment Reviews 1 January 2022, 102:102312. https://doi.org/10.1016/j.ctrv.2021.102312

Efficacy of Eribulin Plus Gemcitabine Combination in L-Sarcomas
Maria Lopez-Alvarez, Cristina Gonzalez-Aguilera, David S. Moura, Paloma Sanchez-Bustos, Jose L. Mondaza-Hernandez, Rafael Ramos, Carolina Castilla, Elena Blanco-Alcaina, Nadia Hindi, Javier Martín-Broto.  Efficacy of eribulin plus gemcitabine combination in L-sarcomas.  Int J Mol Sci. 2022 Dec 30;24(1):680. https://doi.org/10.3390/ijms24010680

Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma
Alessandrini I, Percio S, Zuco V, Naghshineh E, Stacchiotti S, Gronchi A, Pasquali S, Zaffaroni N, Folini M. Telomeres as Therapeutic Targets in Dedifferentiated Liposarcoma. Cancers. 2022 May 25;14(11):2624. https://doi.org/10.3390/cancers14112624

Beyond targeting amplified MDM2 and CDK4 in well differentiated and dedifferentiated liposarcomas: From promise and clinical applications towards identification of progression drivers
Cassinelli G, Pasquali S, Lanzi C. Beyond targeting amplified MDM2 and CDK4 in well differentiated and dedifferentiated liposarcomas: From promise and clinical applications towards identification of progression drivers. Front Oncol. 2022 Sep 2; 12:965261  https://doi.org/10.3389/fonc.2022.965261

Stimulated Raman Scattering Microscopy: Techniques and Applications
Ji-Xin Cheng, Wei Min, Yasuyuki Ozeki, Dario Polli. United States: Elsevier - Health Sciences Division. Paperback ISBN: 9780323851589 (8 December 2021), eBook ISBN: 9780323903370.  https://doi.org/10.1016/C2020-0-01880-3

Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial
Javier Martín-Broto, Maria Lopez-Alvarez, David S. Moura, Rafael Ramos, Paola Collini, Cleofe Romagosa, Silvia Bagué, Salvatore L. Renne, Marta Barisella, Valerie Velasco, Jean-Michel Coindre, Daniel Lopez-Lopez, Joaquin Dopazo, Marco Gambarotti, Luca Braglia, Domenico F. Merlo, Emanuela Palmerini, Silvia Stacchiotti, Vittorio L. Quagliuolo, Antonio Lopez-Pousa, Giovanni Grignani, Jean-Yves Blay, Antonella Brunello, Antonio Gutierrez, Claudia Valverde, Nadia Hindi, Angelo P. Dei Tos, Piero Picci, Paolo G. Casali, Alessandro Gronchi. Molecular Cancer Therapeutics 1 December 2021, 20 (12):2539–2552. https://doi.org/10.1158/1535-7163.mct-21-0315

Data Study Group Final Report: Odin Vision
Timothy S.H. Mun. The Alan Turing Institute 26 November 2021. https://doi.org/10.5281/zenodo.5729340

Olaratumab-induced Biomarker Modulation in Sarcomas-Response
Javier Martín-Broto, Patrick M. Peterson, Gerard J. Oakley, Matteo Ceccarelli, Robin L. Jones. Molecular Cancer Therapeutics 1 October 2021, 20(10):2094. https://doi.org/10.1158/1535-7163.MCT-21-0497

Uncertainty Quantification using U-Net with Monte Carlo Dropout
Timothy S.H. Mun, Simon J. Doran,  Paul H. Huang, Christina Messiou, Matthew D. Blackledge. 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), Quantification of Uncertainties in Biomedical Image Quantification (QUBIQ) Workshop 1 October 2021

Automated Quantification of Blood Microvessels in Hematoxylin and Eosin Whole Slide Images
Azam Hamidinekoo, Anna Kelsey, Nicholas Trahearn, Joanna Selfe, Janet Shipley, Yinyin Yuan. Proceedings of the MICCAI Workshop on Computational Pathology, PMLR 27 September 2021, 156:94-104. https://proceedings.mlr.press/v156/hamidinekoo21a.html

Multimodal Fusion for Radiogenomics Classification of Brain Tumour
Timothy S.H. Mun, Simon J. Doran,  Paul H. Huang, Christina Messiou, Matthew D. Blackledge. 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI),  Brain Tumour Segmentation (BraTS) Challenge Workshop 27 September 2021

Next-generation sequencing for the management of sarcomas with no known driver mutations
Simon Vyse, Khin Thway,  Paul H Huang, Robin L. Jones. Current Opinion in Oncology 1 July 2021, 33(4):315-322. https://doi.org/10.1097/CCO.0000000000000741

The molecular landscape of well differentiated retroperitoneal liposarcoma
Robert Tyler, Mark P. Dilworth, Jonathan James, Daniel Blakeway, Joanne D. Stockton, Dion G. Morton, Phillipe Taniere, David Gourevitch, Anant Desai, Andrew D. Beggs. The Journal of Pathology 22 June 2021, 255(2):132-140. https://doi.org/10.1002/path.5749

Predictive and prognostic transcriptomic biomarkers in soft tissue sarcomas
Eve Merry, Khin Thway, Robin L. Jones, Paul H. Huang. NPJ Precision Oncology 5 March 2021, 5(1):17. https://doi.org/10.1038/s41698-021-00157-4

A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways
Martín Garrido-Rodriguez, Daniel Lopez-Lopez, Francisco M. Ortuno, María Peña-Chilet, Eduardo Muñoz, Marco A. Calzado, Joaquin Dopazo. PLoS Computational Biology 11 February 2021, 17(2):e1008748. https://doi.org/10.1371/journal.pcbi.1008748

Recent advances in the use of stimulated Raman scattering in histopathology
Martin Lee, C. Simon Herrington, Manasa Ravindra, Kristel Sepp, Amy Davies, Alison N. Hulme, Valerie G. Brunton. The Analyst 4 January 2021, 146(3):789-802. https://doi.org/10.1039/d0an01972k

A review of retroperitoneal liposarcoma genomics
Robert Tyler, Kasun Wanigasooriya, Philippe Taniere, Max Almond, Samuel Ford, Anant Desai, Andrew Beggs. Cancer Treatment Reviews 1 June 2020 (epub 28 March 2020), 86(5):102013. https://doi.org/10.1016/j.ctrv.2020.102013

Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down-regulation
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